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Expanded Radiologic Characterization and Long-Term Imaging Follow-Up of Sclerosing Angiomatoid Nodular Transformation
Usama Arbab1, Rajoo Ramachandran1, Sowmya Gopalan2
1Department of Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|February 24, 2026
Summary
Sclerosing angiomatoid nodular transformation (SANT) is a rare, benign splenic vascular lesion. This case highlights its characteristic imaging features and confirms diagnosis via histopathology, emphasizing its importance in differential diagnosis of splenic masses.
Area of Science:
- Pathology
- Radiology
- Hepatology
Background:
- Sclerosing angiomatoid nodular transformation (SANT) is a rare, benign splenic vascular lesion.
- It can mimic malignant splenic lesions on imaging.
- Splenic neoplasms are classified based on their origin in the red or white pulp.
