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Published on: November 15, 2024
Management of Liver Cirrhosis in Percutaneous and Surgical Cardiac Interventions
Cristiano Spadaccio1,2, Antonio Nenna3, Krishna Mehta4
1Cardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.
Insights
Liver cirrhosis significantly increases risks for cardiac interventions. A multidisciplinary heart team approach is crucial for managing patients with cirrhosis undergoing cardiac surgery or procedures.
Area of Science:
- Cardiology
- Hepatology
- Transplantation
Background:
- Liver cirrhosis presents significant risks for cardiovascular intervention outcomes.
- Systemic impairment in cirrhosis leads to increased mortality and complications.
Purpose of the Study:
- To review the impact of liver cirrhosis on cardiac surgery and percutaneous procedure outcomes.
- To provide evidence-based guidance for perioperative management and decision-making in these patients.
Main Methods:
- Literature review analyzing short- and long-term outcomes.
- Extrapolation of key determinants for decision-making.
Main Results:
- Key factors include life expectancy, Child-Pugh/MELD scores, gastroesophageal varices, and hepatic venous pressure gradient (HVPG).
- HVPG >20 mmHg contraindicates surgical approach; gastroesophageal varices require mandatory assessment and treatment.
- Futile treatments should be avoided in advanced cirrhosis.
Conclusions:
- A multidimensional heart team approach is recommended for optimal patient management.
- Involves surgical, cardiologic, anesthesiologic, hepatologic, and medical expertise.
- Careful assessment is vital to improve outcomes for cirrhotic patients undergoing cardiac procedures.
Abstract:
The systemic impairment that accompanies liver cirrhosis is known to carry a significant burden on death and postoperative complications in cardiovascular interventions. This review analyzes the impact of liver cirrhosis on short- and long-term outcomes after cardiac surgery and percutaneous procedures, providing an evidence-based guidance in the decision-making process and perioperative management of these patients. Several parameters should be considered by the heart teams when assessing eligibility, indications for intervention, and perioperative management of these patients. Life expectancy, long-term procedural outcomes, Child-Pugh or the Model for End-Stage Liver Disease score, presence of gastroesophageal varices and hepatic venous pressure gradient were extrapolated as the main determinants in decision making in patients with cirrhosis. Assessment and treatment of gastroesophageal varices is mandatory. Hepatic venous pressure gradient values >20 mm Hg preclude patients from a surgical approach. Considering the poor prognosis of advanced liver cirrhosis, futile treatments should be avoided. A multidimensional heart team approach involving surgical, cardiologic, anesthesiologic, hepatological, and medical considerations is recommended.
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