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Invasive yeast infection in paediatric acute lymphoblastic leukaemia: A report from the multi-international clinical
Andreas H Groll1, Simone Cesaro2, Julia Alten3
1Infectious Disease Research Program, Department of Pediatric Hematology and Oncology and Center for Bone Marrow Transplantation, University Children's Hospital Münster, Münster, Germany.
Abstract:
Prospective data of a large randomized multi-international leukaemia trial revealed an incidence of 1.1% of invasive yeast infections (IYIs) in children with acute lymphoblastic leukaemia. IYIs occurred predominantly during induction chemotherapy, presented as bloodstream infection ± tissue involvement, were due to a variety of yeast and had an attributable mortality of 5.9%.
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