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Respiratory Syncytial Virus After Chimeric Antigen Receptor T-cell Therapy: Risk Factors and Outcomes in a
Maria Isabel Sotelo-Alva1,2, Ofrat Beyar-Katz3, Judy Yan4
1Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, NewYork, New York, USA.
None:
Among 667 CAR-T recipients, the 2-year cumulative incidence of RSV was 7%, with 29% of diagnosed cases progressing to LRTI. Older age and lymphopenia were associated with severity. Most infections (74%) occurred beyond day +100 (median 8 months). No RSV-attributable deaths occurred. Clinical vigilance is warranted, especially during RSV season.
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