Bortezomib-Induced Myocarditis in a Patient With Multiple Myeloma
Adriana Domínguez-Linares1, Ana Karen Nieto-Dolores2, Mauricio Garcia-Cardenas3
1National Institute of Neoplastic Diseases, Lima, Peru; School of Medicine, San Martín de Porres University (USMP), Lima, Peru.
JACC. Case Reports
|February 24, 2026
Summary
Bortezomib, a multiple myeloma drug, can rarely cause myocarditis. Prompt recognition and treatment led to full recovery in a patient, highlighting the importance of early intervention for this rare side effect.
Area of Science:
- Cardiology
- Oncology
- Pharmacology
Background:
- Bortezomib is a proteasome inhibitor used for multiple myeloma and mantle cell lymphoma.
- While effective, bortezomib can rarely cause cardiotoxicity, specifically myocarditis.
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