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Related Experiment Video

Updated: Feb 26, 2026

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

Published on: September 14, 2009

Laser-Assisted OPN Technique for Recalcitrant Multilayer In-Stent Restenosis: A Systematic Approach.

Omar Majwal¹, Vu Hung Quan², Robert Avram¹

¹Department of Interventional Cardiology, Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.

JACC. Case Reports

|February 24, 2026

Summary

The L-OPN technique, combining contrast-enhanced excimer laser coronary atherectomy (ELCA) with OPN balloon angioplasty, offers a viable solution for complex multilayer in-stent restenosis (ISR) when other methods fail. Intravascular imaging guidance is crucial for successful outcomes in these challenging cases.

Area of Science:

Interventional Cardiology
Cardiovascular Research
Medical Device Technology

Background:

Multilayer in-stent restenosis (ISR) with severe stent underexpansion poses a significant clinical challenge.

Keywords:

excimer laser coronary atherectomy in-stent restenosis optical coherence tomography stent underexpansion super-high-pressure balloon

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Conventional interventions often prove insufficient for complex ISR cases, necessitating advanced treatment strategies.