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Updated: May 17, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
[Repetitive transcranial magnetic stimulation for unipolar depression]
Erhan Kavakbasi1,2, Katja Koelkebeck3,4,5, Katharina Marie Steiner4,5
1Klinik für Psychiatrie, Psychotherapie und Psychosomatik, Uniklinik RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland. ekavakbasi@ukaachen.de.
None:
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique that has been established for several years in the treatment of various mental illnesses. The clinical effectiveness for depressive disorders has been proven with good evidence, so that clear guideline recommendations for the use of rTMS have been formulated. It is available as a treatment option in many hospitals and outpatient practices. This article provides a current overview on the use of rTMS in unipolar depression. In addition to the mechanisms of action, data on clinical effectiveness, guideline recommendations and aspects of practical implementation, more recent developments in the field are also presented.
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