Related Experiment Video
Updated: Feb 26, 2026

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
A base deficit levels is a predictor of mortality in the upper gastrointestinal bleedings patients
Gizem Dağdelen1, Cemil Kavalcı2, Elif Hamzaçebioğlu3
1Salihli State Hospital, Emergency Department, Manisa, Turkey.
Aim:
It was aimed to investigate the relationship of shock index, blood pressure index, serum lactate level, and base deficit with 30-day mortality in patients with gastrointestinal bleeding.
Methods:
This prospective, observational, case-control study is conducted in the emergency department of tertiary hospital. A total of 152 patients who were diagnosed with GI bleeding, underwent endoscopy were included in the study. Patients were divided into two groups: those who died within 30 days after GIS bleeding (Group 1) and those who survived (Group 2). To determine the independent factors affecting mortality, variables with p < 0.1 in intergroup comparisons were included in the model, and logistic regression analysis was performed. A p-value of <0.05 was considered significant.
Results:
The median base deficit of patients who died was 9.60 (3.20) mEq/L, while the median base deficit of surviving patients was 2.40 (2.80) mEq/L. The base deficit variable was alone found to be effective in determining 30-day mortality in patients with GIS bleeding.
Conclusion:
According to result of study, Base deficit value alone was found to be significant in predicting 30-day mortality.
Related Concept Videos
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
Esophageal Varices-I: Introduction
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

