A novel all-in-one dynamic wrinkle evaluation system: Development, validation and application in cosmetic industries

Area of Science:

• Dermatology and cosmetic science
• Medical imaging and computer vision
• Biomedical engineering

Background:

• Assessing the efficacy of anti-wrinkle skincare products traditionally relies on static facial images.
• Dynamic wrinkle assessment offers a more comprehensive evaluation of skin aging and treatment outcomes.
• There is a need for standardized, reliable systems for objective dynamic wrinkle analysis.

Purpose of the Study:

• To develop and validate a novel, integrated dynamic wrinkle assessment system.
• To utilize standardized, real-time, multi-angle facial imaging and video.
• To explore its application in evaluating the anti-wrinkle efficacy of skincare products.

Main Methods:

• Developed a system integrating a high-precision positioning apparatus with synchronized, multi-angle high-speed cameras.
• Implemented a novel algorithm for selecting analysis frames based on angular congruence for longitudinal consistency.
• Validated system reproducibility and accuracy using the intraclass correlation coefficient (ICC) and assessed feasibility in an 8-week efficacy trial.

Main Results:

• The system demonstrated high inter-rater reliability (ICC >0.70) among 35 Chinese women, with ICC values exceeding 0.900 for key facial areas.
• Successfully detected and quantified significant improvements (p < 0.05) in both static and dynamic wrinkles in an anti-aging efficacy trial (n=42).
• The system proved feasible and effective in assessing anti-wrinkle cream efficacy over 8 weeks.

Conclusions:

• Successfully developed and validated an all-in-one dynamic wrinkle photo grading evaluation system.
• The system enables personalized assessment of treatment outcomes for topical cosmetic products.
• High accuracy offers a new approach for assessing anti-aging skincare effects, surpassing traditional static methods.