Related Experiment Video

Updated: Feb 26, 2026

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.8K

APOE-ε4 genotype and western diet synergistically aggravate synaptic dysfunction in Alzheimer's disease via D-serine

M Matos1, A Oliveira2, I Matias2

  • 1Univ. Bordeaux, INSERM, Neurocentre Magendie, U1215, Bordeaux, F-33000, France. marco.ledbetter@gmail.com.

Alzheimer'S Research & Therapy
|February 24, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
d-serineAPOE-ε4APP/PS1 miceAlzheimer’s diseaseGene-environment interaction.HippocampusNMDARSynaptic plasticityWestern diet

More Related Videos

A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes
06:43

A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes

Published on: February 5, 2018

12.8K
A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

8.4K

Related Experiment Videos

Last Updated: Feb 26, 2026

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.8K
A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes
06:43

A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes

Published on: February 5, 2018

12.8K
A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

8.4K

Related Concept Videos

Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.9K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.9K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

1.1K
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
1.1K

Articles linked to this work by shared authors, journal, and citation graph.

Nanoplastics influence on toxic metal bioaccumulation and antioxidant responses in Lactuca sativa L. irrigated with treated wastewater.

The Science of the total environment·2026

Educational actions and group physiotherapy on the risk of falls in the older adults: A randomized clinical trial.

Rehabilitacion·2026

Predicting Acetabular Fixation Failure and Bone Loss in Total Hip Arthroplasty: A Combined In Silico and In Vitro Approach.

The Journal of arthroplasty·2025

Feeding sunflower oil enriched with bromoform from Asparagopsis taxiformis impacts young bulls' growth, health, enteric methane production and carbon footprint.

Animal : an international journal of animal bioscience·2025

Seaweed as a climate fix for meat and dairy production: an LCA perspective.

Scientific reports·2025

Nanolabels for biosensors based on lateral flow immunoassays.

Analytica chimica acta·2025

Enhancing Alzheimer's disease diagnosis in primary care through targeted screening of people at risk of developing dementia - study design and feasibility assessment of the PREDEM primary care study.

Alzheimer's research & therapy·2026

A third-generation, high-affinity biparatopic anti-tau antibody inhibits intracellular tau aggregation seeded by Alzheimer's brain extracts.

Alzheimer's research & therapy·2026

Association of self-reported hearing loss and tinnitus with brain structure and cognitive function: a population-based cross-sectional analysis from the Study of Health in Pomerania (SHIP).

Alzheimer's research & therapy·2026

The UNC13A cryptic exon associates with cognitive impairment in Alzheimer's disease.

Alzheimer's research & therapy·2026

Semantic fluency predicts survival of memory clinic patients.

Alzheimer's research & therapy·2026

SuperAging is not the inverse of common-variant Alzheimer's risk: evidence across genetic ancestries.

Alzheimer's research & therapy·2026

Parathyroid Carcinoma and Primary Hyperparathyroidism: Trends and Outcomes.

Endocrine-related cancer·2026

Food Away From Home and Body Mass Index: Insights From a Quantile Regression Analysis of NHANES 2011-2020.

BioMed research international·2026

A diethylene glycol oligomer squalene derivative modulates metabolic gene expression in ob/ob mice.

EXCLI journal·2026

Upper gastrointestinal endoscopy features and Helicobacter pylori infection among patients with type 2 diabetes mellitus presenting with dyspepsia: A cross-sectional observational study.

Medical journal, Armed Forces India·2026

Study of non-alcoholic fatty liver disease in human immunodeficiency virus patients by controlled attenuation parameter.

Medical journal, Armed Forces India·2026

Association of rs429358 and rs7412 polymorphism in apolipoprotein E gene with the severity of neuropathy among type 2 diabetes patients.

Medical journal, Armed Forces India·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us