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From molecular logic to therapeutic modulation: advances in Ub/UBL signalling

Benjamin M Foster1, Chiara Maniaci2

  • 1Manchester Cancer Research Centre (MCRC), Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 555 Wilmslow Road, Manchester M20 4GJ, U.K.

Essays in Biochemistry
|February 25, 2026
PubMed
Summary

Ubiquitin (Ub) and ubiquitin-like proteins (UBLs) regulate cell signaling in processes like DNA repair and immune defense. Advances reveal their versatile roles and therapeutic potential in targeted protein degradation and disease.

Keywords:
post translational modificationtherapeuticsubiquitin signalling

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