Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Could Exosomes be a Promising Therapy to Accelerate Wound Healing and Skin Regeneration in Ischemic Nasal Flaps?

Aesthetic surgery journal. Open forum·2025

Same author

Dexamethasone Mesotherapy: An Alternative for Keloid Treatment in Hispanic Skin.

Plastic and reconstructive surgery. Global open·2024

Same author

Percutaneous Intradermal Purse-String closure for Correction of Male Tuberous Nipple-Areola Complex Deformity.

Aesthetic plastic surgery·2021

Same author

Empathy Levels of Dental Faculty and Students: A Survey Study at an Academic Dental Institution in Chile.

Journal of dental education·2019

Same author

Further Clarification About "Back to Basics: Could the Preoperative Skin Antiseptic Agent Help Prevent Biofilm-Related Capsular Contracture?"

Aesthetic surgery journal·2019

Same author

Back to Basics: Could the Preoperative Skin Antiseptic Agent Help Prevent Biofilm-Related Capsular Contracture?

Aesthetic surgery journal·2018

Search research articles

Related Experiment Video

Updated: Feb 26, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

Exploring Exosomes for Pediatric Ischemic Auricular Flap Repair.

Jenny Carvajal¹, Melissa Carvajal²

¹From the Private Practice, Medellin, Colombia.

Plastic and Reconstructive Surgery. Global Open

|February 25, 2026

Summary

This summary is machine-generated.

Rosa damascena stem cell-derived exosomes safely treated a pediatric ischemic ear flap, promoting complete skin regeneration. This suggests exosomes are a promising therapeutic option for children with traumatic avulsions and compromised skin flaps.

Area of Science:

Regenerative Medicine
Wound Healing
Tissue Engineering

Background:

More Related Videos

Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice

Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice

Published on: April 10, 2019

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

Published on: June 8, 2017

Related Experiment Videos

Last Updated: Feb 26, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice

Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice

Published on: April 10, 2019

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

Published on: June 8, 2017

Upper ear avulsions can lead to ischemic skin flaps and delayed healing due to compromised vascularity.
Vascular Endothelial Growth Factor (VEGF) is crucial for angiogenesis and tissue repair, especially in pediatric wound healing.
Exosomes, particularly those derived from stem cells, are emerging as key mediators in regenerative medicine for skin repair.