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Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

455
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
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Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

834
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
442
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

768
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

392
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Transformative global models for CKD care: case studies and strategies.

James O Burton1, Andrew H Frankel2, Katherine Kwon3

  • 1Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

Clinical Kidney Journal
|February 25, 2026
PubMed
Summary

Early diagnosis and intervention are key for managing chronic kidney disease (CKD). Implementing global initiatives and tailored strategies can improve CKD care and patient outcomes worldwide.

Keywords:
best practicechronic kidney disease (CKD)guideline-directed medical therapy (GDMT)managementsodium-glucose cotransporter 2 (SGLT2) inhibitors

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Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Chronic kidney disease (CKD) affects 10% of adults globally, increasing cardiovascular disease and type 2 diabetes risk.
  • Low adherence to CKD management guidelines, especially for sodium-glucose cotransporter 2 inhibitors (SGLT2is), hinders effective patient care.
  • Timely CKD diagnosis and intervention are critical to prevent disease progression and reduce healthcare burdens.

Purpose of the Study:

  • To address the gap in CKD guideline adherence by highlighting practical solutions for improved clinical practice.
  • To present a 'call-to-action' for healthcare systems and providers to enhance global CKD management.
  • To showcase successful global initiatives transforming CKD care across the entire management pathway.

Main Methods:

  • Review and synthesis of eight diverse 'Champions of Change' initiatives from various health systems.
  • Analysis of innovative and transformative solutions implemented across the CKD management pathway.
  • Identification of core principles for adapting successful CKD management models.

Main Results:

  • Successful initiatives demonstrate the potential of tailored, context-specific strategies in CKD care.
  • Implementation of proactive screening, risk stratification, and multidisciplinary collaboration improves outcomes.
  • Knowledge-sharing and patient-centered approaches are vital for effective CKD management.

Conclusions:

  • Adopting core principles from successful initiatives can help healthcare systems improve CKD management.
  • Tailored strategies are essential for advancing global efforts in preventing CKD progression.
  • Improved CKD management through practical solutions leads to better patient outcomes and reduced health system burden.