Related Experiment Video
Updated: Feb 26, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Developmental Trajectories of Nonsuicidal Self-Injury and Risk for Suicide Attempt
Amanda J Thompson1, Katherine Sarkisian1, Elyse N Llamocca1,2
1The Center for Suicide Prevention and Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Objective:
Suicide attempt (SA) risk is especially high among youth with early nonsuicidal self-injury (NSSI) onset and persistent NSSI. Still, few youth experience persistent NSSI, and few attempt suicide. Identifying which youth follow specific NSSI trajectories and which NSSI trajectories are at higher risk for SA has strong potential to inform more targeted early suicide risk identification and prevention. The present study aimed to identify NSSI trajectories, identify characteristics forecasting which NSSI trajectories youth followed, and compare SA risk across trajectories.
Method:
A subsample of youth (N = 2,524) with at least 1 NSSI event before typical onset was retrospectively identified. Youth were followed for 4 years (ages 9-14 years) using the first 5 annual assessments from the Adolescent Brain Cognitive Development℠ (ABCD) Study (release 5.1).
Results:
Latent-class growth modeling identified 2 subgroups of youth following distinct NSSI trajectories. The earlier-onset group (15%, mean [SD] age at onset = 9.83 [0.59] years) experienced baseline limited NSSI. The later-onset group (85%, mean [SD] age at onset =11.63 [1.60] years) had moderate risk for more than 1 NSSI endorsement. The later-onset group was significantly more likely to attempt suicide than the earlier-onset group (21% vs. 17% reported ≥1 SAs). Sex, psychopathology, family conflict, and positive parenting predicted group membership and SA risk.
Conclusion:
SA risk among youth with early-onset or persistent NSSI was high; however, risk was slightly higher for youth with persistent NSSI. Whereas youth and family characteristics may forecast which NSSI trajectories youth follow, clinical implications of this research support children with NSSI are at risk for SA and may need continued monitoring and intervention. Findings support promoting broad public health awareness of SA risk in youth with NSSI.
Related Concept Videos
Sources of Self-Esteem I: Family Experience
Erikson's Theory on Socioemotional Development during Adolescence
Self-Esteem
Attachment Styles
Self-Evaluation: Self-Enhancement and Self-Verification
Self-Presentation: Self-Monitoring and Self-Handicapping

