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Improving Skin Lesion Diagnosis: A Hybrid Approach Using Orthogonal Combination of Local Binary Pattern Features and
Nasrin Rahmani1, Hossein Ebrahimnezhad1
1Department of Electrical and Computer Engineering, Sahand University of Technology, Tabriz, Iran.
Journal of Medical Signals and Sensors
|February 25, 2026
Summary
Machine learning aids automated skin diagnosis for early skin lesion detection. Ensemble Extra Trees achieved 97.31% accuracy, improving dermatological patient care.
Area of Science:
- Dermatology
- Medical Imaging
- Machine Learning
Background:
- Increasing global wealth and healthcare expectations drive demand for services.
- Healthcare systems face pressure, necessitating efficient diagnostic solutions.
- Early skin lesion diagnosis is crucial for effective treatment and patient outcomes.
Purpose of the Study:
- To develop a machine learning (ML) model for automated skin lesion diagnosis.
- To focus on early detection of skin lesions for improved patient care.
- To classify eight different types of skin lesions.
Main Methods:
- Utilized Gaussian Mixture Models (GMM) with geometric features for image artifact removal.
- Employed a color descriptor based on hybrid orthogonal local binary patterns for lesion characterization.
- Applied ReliefF feature selection to identify key diagnostic features.
- Evaluated multiple ML models including Decision Tree, Random Forest, k-NN, MLP, and Ensemble Extra Trees (ET).
Main Results:
- Ensemble Extra Trees (ET) demonstrated superior performance in classifying skin lesions.
- Achieved a high accuracy rate of 97.31% with the ET model.
- The selected features significantly contributed to accurate classification.
Conclusions:
- The developed ML approach enhances early skin lesion diagnosis.
- This advancement improves the quality of dermatological patient care.
- Automated diagnosis offers a potential solution to increasing healthcare demands.

