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Updated: Feb 26, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Spirobarbiturates with a pyrrolizidine moiety: synthesis, structure and biological evaluation

Arthur A Puzyrkov1, Andrew S Drachuk2, Ekaterina A Popova3

  • 1Saint Petersburg State University, Universitetskaya nab. 7/9, 199034, St. Petersburg, Russian Federation.

Beilstein Journal of Organic Chemistry
|February 25, 2026
PubMed
Abstract

Keywords:
1,3-dipolar cycloadditionalloxanantiproliferative activityazomethine ylidesmaleimidespyrrolizidine moietyspirobarbituratesthree-component reactions

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