Related Experiment Video

Updated: Feb 26, 2026

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients
07:04

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Published on: February 11, 2017

20.2K

CFTR Modulators and Rare Variants-Leaping from Laboratory Cells to Real World Effectiveness?

Nicholas J Simmonds1,2, Damian G Downey3

  • 1Adult Cystic Fibrosis Centre, Royal Brompton Hospital, part of Guy's and St Thomas's NHS Foundation Trust, London, United Kingdom.

American Journal of Respiratory and Critical Care Medicine
|February 25, 2026
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
08:00

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study

Published on: April 11, 2018

11.2K
Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein
09:59

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Published on: March 9, 2015

12.7K

Related Experiment Videos

Last Updated: Feb 26, 2026

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients
07:04

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Published on: February 11, 2017

20.2K
Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
08:00

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study

Published on: April 11, 2018

11.2K
Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein
09:59

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Published on: March 9, 2015

12.7K

Related Concept Videos

Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

49
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
49

Articles linked to this work by shared authors, journal, and citation graph.

Nutrition and cardiometabolic health in cystic fibrosis: Emerging evidence and research gaps.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Health State Utilities Associated With Treatment Burden in Cystic Fibrosis: A Patient Valuation Study.

CHEST pulmonary·2026

The Diagnostic Complexities of Cystic Fibrosis: When to Think of It and What to Do?

British journal of hospital medicine (London, England : 2005)·2026

Contributors to the heterogeneity of response to CFTR modulators.

The Lancet. Respiratory medicine·2026

Effects of Elexacaftor/Tezacaftor/Ivacaftor on cough frequency, physical activity patterns, and sleep quality in adolescents and adults with cystic fibrosis.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Determinants of early Elexacaftor-Tezacaftor-Ivacaftor use in adults with cystic fibrosis and preserved lung function: insights from a European multicenter survey.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

The Renaissance of Bronchiectasis.

American journal of respiratory and critical care medicine·2026

Systematic evaluation of the DNA repair machinery facilitated the development of efficient genome editing tools for the red yeast Rhodotorula toruloides.

Synthetic and systems biotechnology·2026

Bottom-up reconstruction of synthetic pyrenoids provides insights into the mechanisms and evolution of carbon concentration by EPYC1 proteins.

Nature plants·2026

The heavy ion-induced up-regulation of ZIP14 is mediated by the PKCNrf2 pathway.

Life sciences in space research·2026

Enantioselective Reduction of α,β-Dehydro-α-amido Carboxylic Acid Derivatives by Ene-Reductases.

Organic letters·2026

2-Naphthylmethyl Protecting Group Strategy for Streamlined Synthesis of a Fondaparinux Analogue.

Organic letters·2026

Alternative Polyadenylation in the Brain is Modulated by Chronic Ethanol Exposure in a Sex- and Cell Type-Specific Manner.

Molecular neurobiology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us