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Updated: Feb 26, 2026
Fabricating Nanogaps by Nanoskiving
Published on: May 13, 2013
Making Room at the Nanoscale: A Tangible Perspective on Surface Crowding and Molecular Design
Carina I C Crucho1, Pedro V Baptista1
1Associate Laboratory i4HB - Institute for Health and Bioeconomy and UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal.
We developed a scaled model to visualize nanoparticle surface space, making molecular-level constraints tangible. This aids understanding of nanoparticle functionalization for better experimental design and education.
Area of Science:
- Nanotechnology
- Materials Science
- Biophysics
Background:
- Nanoparticle design relies on molecular-level spatial control.
- Surface functionalization metrics like ligand density are often abstract.
- Visualizing available surface space on nanoparticles is challenging.
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