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A hollow microporous organic network-based nanoprobe for imaging tumor-associated mRNA in living cells
Zhi Yan1,2, Yi-Wen Li1, Rui-Jia Yang1
1School of Pharmaceutical Sciences & Institute of Materia Medica, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, 250117, Jinan, Shandong, China. cxyang@nankai.edu.cn.
Abstract:
A novel hollow-shaped microporous organic network (H-MON)-based nanoprobe was rationally designed and synthesized for survivin mRNA imaging. This work presents a promising strategy for the development of novel MON-based cancer-associated biomarker nanoprobes for the early diagnosis of breast cancer.
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