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Related Experiment Video

Updated: Feb 26, 2026

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions
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"Selective Fasciotomy with Local Flap Interposition for Dupuytren Contracture: A Retrospective Analysis".

Mikio Yagishita1, Yuichi Hirase2, Hironobu Iwashiro2

  • 1. Department of Plastic and Reconstructive Surgery, Kanazawa Medical University, Ishikawa, Japan.

Plastic and Reconstructive Surgery
|February 25, 2026
PubMed
Summary

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A new surgical technique for Dupuytren contracture, involving selective fasciotomy and local flap interposition, shows promising results in restoring finger extension and preventing recurrence. This method offers a low complication rate for patients with this fibroproliferative disorder.

Area of Science:

  • Hand Surgery
  • Orthopedic Surgery
  • Fibroproliferative Disorders

Background:

  • Dupuytren contracture causes progressive finger flexion deformities.
  • Traditional surgical methods have limitations.
  • A novel technique combining selective fasciotomy and local flap interposition was developed.

Purpose of the Study:

  • To evaluate the efficacy and safety of a novel surgical technique for Dupuytren contracture.
  • To assess the ability of the technique to restore finger extension and prevent recurrence.

Main Methods:

  • Retrospective review of 64 patients (90 fingers) treated between 2011 and 2024.
  • Selective division of pathological cords via transverse incisions.
  • Interposition of digitolateral or ulnar parametacarpal flaps to cover skin defects and prevent fascial reconnection.
Keywords:
Digitolateral flapDupuytren contractureLocal flap interpositionRecurrenceRetrospective studiesSelective fasciotomyTreatment outcomeUlnar parametacarpal flap

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An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
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Last Updated: Feb 26, 2026

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An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
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Main Results:

  • All flaps survived with no major complications.
  • At 6 months postoperatively, 90.7% of metacarpophalangeal and 61.7% of proximal interphalangeal joints maintained extension within -5°.
  • No recurrence observed in 23 fingers followed for over 2 years.

Conclusions:

  • The technique demonstrated favorable clinical outcomes with minimal complications.
  • Selective division and flap interposition may reduce fascial reconnection and early recurrence.
  • Further long-term studies are needed to confirm durability and refine indications.