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Published on: May 23, 2025
Pulmonary fibrosis in horses associated with spontaneous Crotalaria juncea intoxication
Andrezza C Andrade1, Silvio M C Fonseca1, Givaldo B Silva Filho1
1Laboratório de Diagnóstico Animal, Universidade Federal Rural de Pernambuco (UFRPE), Rua Dom Manuel de Medeiros s/n, Recife, PE, 52171-900, Brazil.
Abstract:
We report an outbreak of Crotalaria juncea intoxication in horses exhibiting progressive weight loss and respiratory distress in northeastern Brazil. Necropsy revealed firm, non-collapsed lungs with extensive interstitial fibrosis, bronchiolar epithelial hyperplasia with club cells proliferation, and marked pulmonary arterial remodeling. Hepatic lesions consisted primarily of centrilobular necrosis, probably resulting from hypoxic injury related to anemia and prolonged agonic death. Pasture inspection identified significant invasion by shrubs of C. juncea in various phenological stages.
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