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Updated: Feb 28, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Paravalvular Regurgitation After Transcatheter Aortic Valve Replacement: Incidence, Mechanism, and Interventional
Matteo Biroli1, Gilbert H L Tang2, Maurizio Taramasso3
1Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; Department of Interventional, Valvular and Structural Heart Cardiology, Centro Cardiologico Monzino IRCCS, Milan, Italy.
None:
Experience with transcatheter aortic valve replacement (TAVR) techniques is rapidly expanding, driven primarily by technological advances in device design and positive clinical outcomes across various patient populations. Paravalvular leak (PVL), a known complication of TAVR associated with less favorable clinical outcomes, has progressively been addressed with improvements in the sealing mechanisms of transcatheter heart valves and with the development of strategies aimed at mitigating or even eliminating its clinical impact. The aim of this review is to provide a comprehensive overview of PVL after TAVR, examining etiology, risk factors, diagnostic approaches, and management strategies. By synthesizing current evidence and highlighting recent advances, the aim is to contribute to ongoing efforts to optimize TAVR outcomes and reduce the burden of PVL in this rapidly evolving field.
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