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An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Integrative multi-omics analysis of dietary fibre-induced modulations in the composition and function of chicken
Anum Ali Ahmad1, Kellie Watson2, Farina Khattak3
1The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, UK. aahmad3@ed.ac.uk.
Abstract:
The sustainability of poultry farming faces significant challenges due to rising feed costs and competition with human food sources. Dietary fibre offers a promising, cost-effective alternative due to its beneficial impact on gut health. We utilised a multi-omics approach to understand the influence of soluble inulin and insoluble cellulose dietary fibres on the composition and function of caecal microbiota in broilers. High inulin supplementation (4%) significantly altered caecal microbial composition and promoted broader microbial metabolic adaptations, indicating a strong fermentative response to this soluble fibre source. In contrast, high cellulose (4%) had a minimal impact, reflecting its limited fermentability and structural complexity. These findings provide valuable insights into how different fibre types and quantities shape gut microbial communities and their functional potential. A deeper understanding of these interactions will aid in formulating targeted dietary strategies to optimise gut health, nutrient utilisation, and overall poultry performance.
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