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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
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Updated: Feb 28, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
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Diffusion Weighted Fast Spin Echo With RF-Encoded Slabs for Portable Low-Field MRI Systems.

Philip K Lee1, Yueqi Qiu1, Suen Chen1

  • 1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

Magnetic Resonance in Medicine
|February 25, 2026
PubMed
Summary
This summary is machine-generated.

A new diffusion-weighted fast spin echo (DW-FSE) technique offers distortionless, high-SNR imaging on portable MRI systems. This robust method achieves clinically feasible scan times, improving diagnostic capabilities in low-field MRI environments.

Keywords:
clinical low‐field MRIdiffusion MRIdiffusion reconstructionportable MRIslice RF‐encoding

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Area of Science:

  • Magnetic Resonance Imaging
  • Diffusion Weighted Imaging
  • Medical Device Technology

Background:

  • Portable MRI systems offer accessibility but face challenges in image quality and scan time for advanced sequences.
  • Diffusion Weighted Imaging (DWI) is crucial for neurological assessment, but conventional methods like Echo Planar Imaging (EPI) are prone to artifacts and hardware demands.
  • Developing robust DWI techniques for low-field portable MRI is essential for expanding its clinical utility.

Purpose of the Study:

  • To develop a robust diffusion-weighted (DW) acquisition technique for portable MRI systems.
  • To achieve clinically feasible scan times for DW imaging on low-field systems.
  • To overcome limitations of existing DWI methods in portable MRI settings.

Main Methods:

  • A linear reconstruction model was developed for slab diffusion-weighted fast spin echo (DW-FSE) data, incorporating tailored RF-encoding, motion-induced phases, and systematic phase errors.
  • Systematic phase errors were calibrated using a phantom, and the DW-FSE technique was compared to DW-EPI in vivo on a 110 mT portable system.
  • Retrospective undersampling was used to evaluate image quality and diffusivity variation within clinically feasible scan times.

Main Results:

  • The developed RF-encoded slab DW-FSE technique produced trace-weighted images free from distortion artifacts and with 5x smaller voxel sizes compared to DW-EPI.
  • Accurate estimation of motion-induced phases and reduction of ghosting artifacts were achieved by accounting for various phase sources.
  • A scan time of 12 minutes allowed for 12 cm slice coverage with 2.5x2.5x5 mm³ voxel sizes, demonstrating potential for clinical feasibility.

Conclusions:

  • Diffusion-weighted FSE is a robust and distortionless approach for high signal-to-noise ratio (SNR) efficiency DWI on portable MRI systems.
  • This multiband quadratic phase increment DW-FSE technique effectively utilizes low-field strengths, offering advantages over DW-EPI in terms of SAR, peak B1, and hardware dependency.