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The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction

Dominic A Ritacco1, Hamna Shahnawaz1, Antonia Oduguwa1

  • 1Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.

Molecular Cell
|February 26, 2026
PubMed

Keywords:
DNAdamageinnate immunityinterferonintracellular bacterialysosomemitochondrionviruses

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