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The Swedish National Quality Register for Repetitive Transcranial Magnetic Stimulation.

S Melker Hagsäter1,2, Axel Nordenskjöld3, Pia Nordanskog4,5

  • 1Department of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

Acta Psychiatrica Scandinavica
|February 26, 2026
PubMed
Summary

The Swedish National Quality Register for repetitive transcranial magnetic stimulation (rTMS) collects data on depression treatment. This registry supports real-world effectiveness research for rTMS in depression.

Keywords:
depressionepidemiologyquality‐registerrepetitive transcranial magnetic stimulationtheta‐burst stimulation

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Medical Informatics

Background:

  • Repetitive transcranial magnetic stimulation (rTMS) is an established treatment for depression.
  • rTMS is being explored for various other neurological and psychiatric conditions.
  • High-quality data collection is crucial for understanding rTMS effectiveness in real-world settings.

Purpose of the Study:

  • To present the Swedish National Quality Register for rTMS (Q-rTMS).
  • To describe the data collected, organizational structure, and accumulated data volume.
  • To highlight the registry's potential for population-based research.

Main Methods:

  • The Q-rTMS registry collects epidemiological data, standardized rating scales (e.g., MADRS-S, CGI-S, EQ-5D-5L), treatment parameters, and patient-reported outcomes.
  • Data are gathered from multiple rTMS providers across Sweden.
  • The registry structure facilitates longitudinal tracking of treatment outcomes.

Main Results:

  • As of 2024, the Q-rTMS includes data from 3083 individuals and 3842 treatment series from 27 providers.
  • The primary indication for rTMS is depression (74.1%), followed by bipolar disorder (14.2%).
  • Pre- and post-treatment data completeness exceeds 60% for key outcome measures.

Conclusions:

  • The Q-rTMS registry offers extensive coverage and longitudinal outcome data.
  • It is a valuable resource for population-based real-world effectiveness research in rTMS for depression.
  • The registry supports ongoing evaluation and improvement of rTMS treatment.