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Rewriting the viral script: post-translational modifications orchestrating SARS-CoV-2 pathogenesis and immune evasion

Jie Qu1, Minglong Liu1, Chen Zhou2

  • 1Department of Cadre Ward, The First Hospital of Jilin University, Changchun, China.

Frontiers in Microbiology
|February 26, 2026
PubMed
Summary

SARS-CoV-2 uses post-translational modifications (PTMs) to control host cells and infection. Understanding these PTMs offers new therapeutic targets for COVID-19 and future viral threats.

Keywords:
SARS-CoV-2 pathogenesishost–virus interactionspost-translational modificationstherapeutic targetingviral immune evasion

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