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Updated: Feb 27, 2026

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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
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Postparathyroidectomy calciphylaxis in a patient with primary hyperparathyroidism: a rare complication
Akriti Karki1, Lina Alomari2, Joy Halliday2
1The University of Buckingham Medical School, Buckingham MK18 1EG, UK.
JCEM Case Reports
|February 26, 2026
Summary
Nonuremic calciphylaxis (NUC) is rare, especially with primary hyperparathyroidism. This case shows successful conservative management and parathyroidectomy for NUC in a patient without chronic kidney disease.
Area of Science:
- Nephrology
- Endocrinology
- Dermatology
Background:
- Calciphylaxis is a rare, severe condition of subcutaneous calcification and necrosis, typically linked to chronic kidney disease (CKD).
- Nonuremic calciphylaxis (NUC) occurs in patients without CKD, and NUC associated with primary hyperparathyroidism is exceptionally rare, with limited established treatments.
- Primary hyperparathyroidism can cause severe hypercalcemia, posing significant health risks.
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