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Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report
Arif Hasan Chowdhury1, Tania Rahman1, Nazrul Islam1
1Clinical Microbiology and Immunology Laboratory, Office of Executive Director (OED) icddr,b Dhaka Bangladesh.
Abstract:
Candida auris is an emerging multidrug-resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection-control challenges, particularly in low- and middle-income countries. We report a 74-year-old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia. Blood culture yielded Gram-positive budding yeast with inconclusive conventional carbohydrate tests. The isolate was identified as C. auris using Vitek 2 (software v8.01) and confirmed by ITS sequencing (GenBank accession MZ323988). Phylogenetic analysis showed clustering with global strains. Antifungal susceptibility testing indicated resistance to fluconazole and amphotericin B, with susceptibility to echinocandins. Intravenous micafungin was started based on susceptibility results and guideline recommendations. The patient responded gradually to the treatment, recovered fully, and was discharged after 21 days of admission. This case highlights the importance of rapid species-level identification and access to confirmatory molecular testing to guide effective treatment and infection prevention in resource-limited settings.
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