Related Experiment Video
Updated: Feb 27, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Fluoride content in children's dentifrices marketed in Argentina
Ana Sorazabal1, Lidia Ar Valadas2, Angela B Argentieri2
1Universidad de Buenos Aires, Facultad de Odontología, Cátedra de Odontología Preventiva y Comunitaria, Buenos Aires, Argentina. ana.sorazabal@odontologia.uba.ar.
Introduction:
Fluoridated dentifrices are the most widely used formulations for caries prevention and control. However, there is great concern regarding legislation on the use of fluoride formulations in early childhood from the standpoint of avoiding increased risk of fluorosis while at the same time achieving a concentration that ensures anticaries activity.
Aim:
The aim of this study was to evaluate the stability of fluoride concentration in the main children's toothpaste brands marketed in Argentina.
Materials And Method:
Twenty different brands of children's toothpaste were evaluated by analyzing the concentration of total fluoride (TF), total soluble fluoride (TSF) and ionic fluoride (IF) in two or three samples of each brand. Each sample was analyzed in duplicate using an ion-specific electrode calibrated with fluoride standards, and the results were expressed in ppm (µg F/g).
Results:
TF was found to be lower than stated by the manufacturer in 85% of the brands analyzed. TF concentration found in fluoride toothpastes ranged from 651.5 to 1090.4 μg/ml F-, while TSF ranged from 504.2 to 915.5 μg/ml F, and IF from 298.6 to 838.2 μg/ml F-.
Conclusions:
The formulation and fluoride content in children's toothpastes marketed in Argentina vary greatly according to brand. In all the samples, TF concentration was lower than 1500 ppm F-, and TSF concentration was lower than 1000 ppm F-, the minimum amount necessary to ensure anticaries effect. This indicates the need for improved formulations and regulations.
More Related Videos
08:20Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
09:34Semi-Automated Planimetric Quantification of Dental Plaque Using an Intraoral Fluorescence Camera
Published on: January 27, 2023
Related Concept Videos
Minerals
Major...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Local Anesthetics: Chemistry and Structure-Activity Relationship
Drug Dosing: Infants and Children
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...