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Updated: Feb 27, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
Wernicke's encephalopathy after laparoscopic sleeve gastrectomy.
Mikel Rojo Abecia1, María Marqueta de Salas1, Ana Álvarez Cuiñas1
1Department of Bariatric and Metabolic Surgery, General Surgery Service, Hospital Universitario Severo Ochoa, Leganés, Spain.
Sleeve gastrectomy can lead to Wernicke's encephalopathy due to thiamine deficiency, even without malabsorption. Prompt diagnosis and intravenous thiamine treatment are crucial for recovery and preventing severe complications.
Area of Science:
- Neurology
- Gastroenterology
- Nutritional Science
Background:
- Wernicke's encephalopathy (WE) is a serious neurological condition.
- Bariatric surgery, particularly malabsorptive procedures, is a known risk factor for WE.
- Sleeve gastrectomy is generally considered lower risk, but WE can still occur.
Purpose of the Study:
- To present a case of Wernicke's encephalopathy following sleeve gastrectomy.
- To highlight the importance of clinical suspicion in diagnosing WE post-sleeve gastrectomy.
- To emphasize the effectiveness of timely thiamine repletion.
Main Methods:
- Case report of a 48-year-old patient with obesity (BMI 55).
- Patient underwent sleeve gastrectomy and cholecystectomy.
- Diagnosis based on clinical presentation (vomiting, confusion, amnesia, limb weakness) and low thiamine levels.
Main Results:
- The patient presented with symptoms consistent with Wernicke's encephalopathy after surgery.
- Low blood thiamine levels confirmed the diagnosis.
- Intravenous thiamine treatment led to adequate clinical improvement.
Conclusions:
- Wernicke's encephalopathy is a potential complication of sleeve gastrectomy, irrespective of malabsorption.
- Early clinical suspicion and biochemical confirmation are vital for prompt treatment.
- Intravenous thiamine administration is effective in managing WE and preventing long-term sequelae.
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