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Updated: May 7, 2026
Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples
Published on: July 6, 2014
Surgically Treated Cervical Cancer in Manitoba: A Retrospective Study of the Impact of Geography on Care
Nora-Beth Mercier1, Yuliia Khudina1, Lesley Roberts1
1Division of Gynecologic Oncology, Winnipeg Women's Hospital, University of Manitoba, Winnipeg, MB R3E 0L8, Canada.
Background/Objectives:
Cervical cancer outcomes based on geographic location of residence reveal inconsistent patterns, and most of the evidence is from the United States. This retrospective study aimed to investigate whether there existed a difference in overall survival (OS) and recurrence-free survival (RFS) between individuals living within a Canadian city with a tertiary care centre versus those living remotely within a large catchment area (up to >1000 km travel distance), including a sizeable rural component.
Methods:
Surgically treated cervical cancer patients from 2000 to 2016 were included. Patients were treated with either radical hysterectomy, trachelectomy, or simple hysterectomy. Adjuvant treatment was provided depending on surgical pathology. OS and RFS were estimated using Kaplan-Meier curves and cumulative incidence curves.
Results:
Two hundred and eighty-two patients with surgically treated cervical cancer were included: 185 patients living within urban city limits and 97 patients living rurally. There were no significant baseline differences between groups. No significant difference in OS or RFS was found, even after adjusting for death as a competing risk for RFS. The median time to surgery for residents living within versus outside the city was 84 vs. 66 days, respectively, although this difference was not statistically significant (p = 0.3179).
Conclusions:
This is the first Canadian study to examine an association between survival and distance to care for cervical cancer.
