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Cardiac Catheterization for Coronary Artery Fistulas in Children: Evaluation, Management, and Outcomes-A
Hayrettin Hakan Aykan1,2, Nilay Korgal1, Alpay Çeliker3
1Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara 06100, Türkiye.
Insights
Coronary artery fistulas (CAFs) in children are rare. Transcatheter closure is safe and effective for selected cases, while conservative management suits small, insignificant fistulas, guiding individualized care.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Interventional Cardiology
Background:
- Coronary artery fistulas (CAFs) are rare congenital anomalies in children.
- Optimal management of asymptomatic CAFs and long-term outcomes are debated.
Purpose of the Study:
- To evaluate the safety and efficacy of transcatheter closure for pediatric CAFs.
- To assess outcomes of conservative management for select pediatric CAFs.
- To analyze institutional changes in clinical approach and device selection over time.
Main Methods:
- Retrospective evaluation of pediatric patients (<18 years) with CAFs undergoing cardiac catheterization (2003-2022).
- Analysis of demographic, clinical, angiographic, procedural, and follow-up data.
- Classification of fistulas using a modified Sakakibara system.
Main Results:
- Forty-two patients were included; 80.9% were asymptomatic.
- Transcatheter closure was technically successful in 92% of 25 attempted cases.
- Complete occlusion was achieved in 61% immediately, exceeding 90% during follow-up; no major complications or ischemic outcomes were observed.
Conclusions:
- Transcatheter closure is a safe and effective option for selected pediatric CAFs.
- Conservative follow-up is appropriate for small, hemodynamically insignificant CAFs.
- Individualized, anatomy-guided management is supported for pediatric CAFs.
Abstract:
Coronary artery fistulas (CAFs) are rare congenital coronary anomalies in children and are frequently detected incidentally; however, the optimal management of asymptomatic cases and long-term outcomes remain debated. We retrospectively evaluated patients <18 years who underwent cardiac catheterization and coronary angiography for CAF at a single tertiary center between 2003 and 2022, analyzing demographic, clinical, angiographic, procedural, and follow-up data; fistulas were classified using a modified Sakakibara system, and temporal changes in institutional clinical approach and device selection were also assessed. Forty-two patients (mean age 7.4 ± 5.9 years) were included, most of whom were asymptomatic (80.9%); the left coronary artery was the most frequent origin and 85% drained to right-sided chambers. Transcatheter closure was attempted in 25 patients and was technically successful in 23 (92%); complete occlusion was achieved angiographically in 61% immediately and exceeded 90% during follow-up due to spontaneous resolution of residual shunts. One patient required surgery for persistent moderate residual flow, and no major procedural complications, thrombotic events, or ischemic outcomes were observed. In selected children, transcatheter CAF closure is safe and effective, while conservative follow-up appears appropriate for small, hemodynamically insignificant fistulas, supporting individualized, anatomy-guided management.
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