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Updated: Feb 27, 2026

Harvesting of Peroneus Longus Tendon Autograft
Published on: September 2, 2025
No Difference in Knee Pain Between Bone-patellar Tendon-bone and Hamstring Autograft at 2-year Follow-up
Nicholas F Banfield1, Rebekah M Kleinsmith2, Haley D Puckett3
1Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota.
Bone-patellar tendon-bone (BPTB) autografts for anterior cruciate ligament reconstruction (ACLR) did not result in worse knee pain compared to hamstring (HT) autografts. This 2-year study found no significant differences in patient-reported pain outcomes between the two graft types.
Area of Science:
- Orthopedic Surgery
- Sports Medicine
- Biomedical Engineering
Background:
- Previous studies suggest bone-patellar tendon-bone (BPTB) autografts may cause more anterior knee pain after anterior cruciate ligament reconstruction (ACLR).
- Hamstring (HT) autografts are an alternative, but direct comparisons of pain outcomes are crucial.
Purpose of the Study:
- To compare patient-reported outcome measures (PROMs) at 2-year follow-up for ACLR using BPTB versus HT autografts.
- To specifically assess differences in knee pain between the two graft types.
Main Methods:
- Retrospective cohort study of 411 patients undergoing primary ACLR (2009-2021).
- Collected 2-year PROMs including Knee Injury and Osteoarthritis Outcome Score (KOOS) and KOOS pain subscale.
- Utilized descriptive analyses, t tests, chi-squared tests, and ANOVA for statistical analysis (P ≤ .05).
Main Results:
- No significant difference in 2-year improvement or final KOOS pain subscale scores between BPTB and HT autografts (P > .05).
- Baseline overall KOOS was higher in the BPTB group, but 2-year change in KOOS was higher in the HT group (P < .001, P = .040).
- Overall KOOS at final follow-up did not differ significantly between BPTB and HT autografts (P = .136).
Conclusions:
- ACLR using BPTB autografts is not associated with worse knee pain compared to HT autografts at 2-year follow-up.
- These findings challenge previous assumptions about BPTB graft-associated pain.
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