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Aggregate Consumer Exposure and Risk Assessment in the EU-A Case Study.
Jan Oltmanns1, Christoph Scheibelein2, Fabian A Grimm3
1Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Klarastraße 63, 79106 Freiburg, Germany.
Toxics
|February 26, 2026
Summary
This study introduces a new method for aggregate chemical risk assessment in the EU, combining exposure from various sources. The approach ensures comprehensive evaluation and transparency for consumer safety.
Area of Science:
- Environmental Science
- Toxicology
- Risk Assessment
Background:
- Current EU chemical exposure assessments are product-specific, lacking aggregation across sources.
- Integrated approaches offer improved comprehensive risk evaluation and value chain transparency.
Purpose of the Study:
- To develop and demonstrate aggregate consumer exposure and risk assessment methods.
- To establish a uniform risk metric for comprehensive evaluation.
Main Methods:
- Calculated exposure and risk per pathway using the risk characterization ratio (RCR).
- Aggregated pathway-specific RCRs to determine overall risk.
- Normalized key input values to body weight for population-specific differences.
Main Results:
- Demonstrated practical applicability using the antioxidant ethylene bis[3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate] (Hostanox® O 3).
- Aggregate RCRs were below one for all population groups studied.
- Infants and toddlers exhibited the highest aggregate RCRs due to higher consumption and skin surface area.
Conclusions:
- The developed methodology provides a transparent and applicable approach for aggregate exposure and risk assessment.
- This method can be utilized by industry stakeholders and authorities for various substances.
- The study informs the development of aggregate exposure and risk methods within EU regulatory frameworks.
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