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Quantum Sensing for Precision Organ Aging Assessment
Jingyi Niu1,2, Ya Peng3, Lin Yin4
1The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha 410008, Hunan, China.
Aging and Disease
|February 26, 2026
Summary
Organ biological age (OBA) offers a better measure of aging than chronological age. Quantum sensing technology promises non-invasive, real-time OBA assessment for proactive health management.
Area of Science:
- Biogerontology
- Quantum Sensing
- Precision Medicine
Background:
- Chronological age is an insufficient metric for physiological decline due to heterogeneous organ aging.
- Current organ biological age (OBA) assessments capture aging outcomes, not onset, limiting clinical utility.
- Existing methods rely on invasive sampling and lack sensitivity to early, subtle microenvironmental changes.
Purpose of the Study:
- To review molecular and systemic mechanisms of organ-specific aging.
- To evaluate current multi-omics and imaging approaches for OBA assessment.
- To introduce quantum sensing as a novel technology for OBA.
Main Methods:
- Review of existing literature on organ aging mechanisms and assessment techniques.
- Exploration of quantum sensing principles (coherence, spin-based detection) for biological applications.
- Discussion of AI integration with quantum sensors for dynamic OBA tracking.
Main Results:
- Quantum sensors offer non-invasive, real-time detection of subtle organ microenvironmental signals.
- Quantum sensing enables high-frequency tracking of organ aging trajectories.
- AI-integrated quantum sensing can dynamically quantify aging pace.
Conclusions:
- Quantum-enabled OBA assessment represents a paradigm shift in precision aging medicine.
- This technology facilitates proactive and individualized health management.
- It bridges molecular energetics and organ physiology for early disease intervention.

