Related Experiment Video

Updated: Feb 28, 2026

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
06:19

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

10.9K

Cumulative High-Risk Pregnancy Complications and Stunting Risk in Indonesian Children Younger Than 5 Years:

Widyawati Widyawati1, Hafifah Maulia Ristandiati2

  • 1Department of Pediatric and Maternity Nursing, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Jl. Farmako, Sekip Utara, Kec. Depok, Kabupaten Sleman, Daerah Istimewa Yogyakarta, 55281, Indonesia, 62 274 545674.

Asian/Pacific Island Nursing Journal
|February 26, 2026
PubMed

Insights

High-risk pregnancy complications significantly increase stunting risk in Indonesian children. Addressing cumulative prenatal risks through integrated antenatal care is crucial for prevention.

Area of Science:

  • Pediatric Health
  • Maternal Health
  • Public Health Nutrition

Background:

  • Stunting affects 21.6% of Indonesian children under five.
  • High-risk pregnancies (HRPs) are a potential risk factor for stunting.
  • Prenatal exposures can impact long-term health and disease susceptibility (Developmental Origins of Health and Disease framework).

Purpose of the Study:

  • To investigate the cumulative impact of HRP complications on stunting risk in Indonesian children.
  • To control for socioeconomic factors in the analysis.

Main Methods:

  • Retrospective study in Sleman Regency, Indonesia.
  • Analyzed 450 children (12-59 months) – 300 with stunting, 150 without.
  • Used multivariate logistic regression, adjusting for maternal education, family income, and antenatal care (ANC) visits.

Main Results:

  • Mothers of children with stunting had higher rates of HRP complications (68.7% vs 32%).
  • Multiple HRP complications (≥2) showed the strongest association with stunting (aOR 5.80).
  • Anemia (aOR 3.21) and preeclampsia (aOR 4.37) were also significant risk factors.

Conclusions:

  • A dose-response relationship exists between cumulative HRP complications and stunting, supporting the Developmental Origins of Health and Disease hypothesis.
  • Current antenatal care protocols focusing on single risk factors may be insufficient.
  • Integrated prenatal care addressing cumulative risks is vital for stunting prevention in Indonesia.
Abstract

Keywords:
Developmental Origins of Health and Diseasechild nutrition disordershigh-risk pregnancymaternal healthpregnancy complicationsstunting

More Related Videos

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

785
Assessment of Child Anthropometry in a Large Epidemiologic Study09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

28.0K

Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.4K
Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
22.6K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.9K
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
288
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
2.3K
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
60