Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

65
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
65

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rates, Timing, and Predictors of Retreatment Across Risk-Cohorts in Retinopathy of Prematurity: Intravitreal Bevacizumab Injection vs Laser.

American journal of ophthalmology·2026
Same author

Systemic Anemia and the Risk of Diabetic Macular Edema and Anti-VEGF Injections.

Ophthalmology. Retina·2026
Same author

Dopamine-Enhancing Therapies and Risk of Neovascular AMD Conversion: A Target Trial Emulation.

American journal of ophthalmology·2026
Same author

Longitudinal Trends of Intraocular Lens Dislocation in a Federated Electronic Health Record Network.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Non-tobacco nicotine use and the risk of cataract development.

Annals of epidemiology·2026
Same author

Diabetic Retinopathy Outcomes Among Unhoused Individuals: A Big Data Analysis.

Retina (Philadelphia, Pa.)·2026

Related Experiment Video

Updated: May 6, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

22.4K

Association Between Retinal Vein Occlusion and Epiretinal Membrane Development.

Abdulkader Almosa1, Ahmed M Alshaikhsalama2, Ahmed Abdi2

  • 1From the School of Medicine (A.A.), Texas Tech University Health Sciences Center, Lubbock, Texas, USA.

American Journal of Ophthalmology
|February 26, 2026
PubMed
Summary
This summary is machine-generated.

Retinal vein occlusion (RVO) significantly increases the risk of epiretinal membrane (ERM) formation within three months. Surgical intervention for ERM typically occurs later, with anti-VEGF treatment potentially delaying this timing.

More Related Videos

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

3.3K
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

2.7K

Related Experiment Videos

Last Updated: May 6, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

22.4K
Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

3.3K
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

2.7K

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Vascular Disorders

Background:

  • Retinal vein occlusion (RVO) is a significant cause of vision loss.
  • Epiretinal membrane (ERM) formation can lead to visual distortion and decreased acuity.
  • The relationship between RVO and subsequent ERM development requires further temporal analysis.

Purpose of the Study:

  • To evaluate the temporal association between retinal vein occlusion (RVO) and the development of epiretinal membrane (ERM).
  • To assess the timing of subsequent ERM peel surgery in RVO patients.
  • To compare ERM development and peel timing in treated versus untreated RVO cohorts.

Main Methods:

  • Retrospective cohort study utilizing a national clinical database.
  • Propensity score matching (PSM) was applied to compare RVO patients (BRVO and CRVO) with matched controls.
  • Relative risk (RR) of incident ERM formation and ERM peel was analyzed at multiple time points up to five years.

Main Results:

  • Both BRVO and CRVO cohorts showed a significantly higher risk of ERM formation at three months post-RVO compared to controls (RR 4.54 and 4.90, respectively).
  • ERM peel risk peaked at one year for BRVO (RR 3.83) and three years for CRVO (RR 3.91).
  • Anti-VEGF treatment was associated with higher ERM rates at three months (BRVO-T RR 5.60, CRVO-T RR 6.80) and a later peak for ERM peel (5 years).

Conclusions:

  • ERM typically forms within three months following RVO.
  • Surgical intervention for ERM occurs later, with timing influenced by RVO type and anti-VEGF treatment.
  • Treated RVO patients had an elevated ERM risk, potentially due to baseline disease severity.