[A Case of Liver Metastatic Recurrence of Transverse Colon Cancer Responding to Capecitabine+Bevacizumab Therapy]

The patient was a 78‒year‒old woman. A liver tumor was detected on abdominal computed tomography(CT)performed for follow‒up after breast cancer surgery. Further examination revealed transverse colon cancer and liver metastases; therefore, transverse colon resection with D3 lymph node dissection and resection of the central 2 segments of the liver were performed. Four months later, liver recurrence was found on CT, which was diagnosed as unresectable, and chemotherapy was planned. Chemotherapy with capecitabine+oxaliplatin+bevacizumab was initiated. The capecitabine and oxaliplatin dosages were reduced due to adverse events. The CT scan showed PR; therefore, maintenance therapy with capecitabine+bevacizumab was initiated. The recurrent tumor continued to gradually shrink, and only a cystic lesion was observed on CT. CT performed 4 years and 1 month after the initiation of chemotherapy showed that the cystic lesion had almost disappeared from the liver. We believe that the factor contributing to the long‒term response in this case was the appropriate dose reduction and cessation of chemotherapy.