Molecular insights into mRNA export regulation by the human TREX-2 complex

Xing Gong1, Ran Tao1, Xiaofei Ge2

  • 1Center for Reproduction and Genetics, Department of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, MOE Key Laboratory for Cellular Dynamics, Hefei National Research Center for Interdisciplinary Sciences at the Microscale, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, The USTC RNA Institute, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230027, China.

Nature Communications
|February 26, 2026
PubMed
Summary

The TREX-2 complex interacts with UAP56, revealing its structure and function in mRNA export. This interaction stimulates UAP56

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