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Developmental Foundations of Psychosocial Interventions in Pediatric Oncology: A Lifespan Framework for Resilience

Antonios I Christou1, Georgia Kalfadeli1, Flora Bacopoulou2

  • 1Department of Special Education, University of Thessaly, 38221 Volos, Greece.

Children (Basel, Switzerland)
|February 27, 2026
PubMed

Insights

Developmentally tailored psychosocial interventions significantly improve cognitive and social outcomes for children with cancer. Focusing on long-term, culturally sensitive programs is key for enhancing effectiveness in pediatric oncology care.

Area of Science:

  • Pediatric Oncology
  • Developmental Psychology
  • Psychosocial Care

Background:

  • Pediatric cancer survival rates have increased due to innovative treatments.
  • Significant challenges persist in cognitive and psychosocial development for childhood cancer patients.
  • Evaluating psychosocial interventions is crucial for improving quality of life.

Purpose of the Study:

  • To comprehensively review psychosocial interventions for pediatric cancer patients.
  • To offer novel insights into intervention strategies and their effectiveness.
  • To evaluate interventions across diverse pediatric oncology contexts.

Main Methods:

  • Systematic literature search (2000-2024) across major databases.
  • Included controlled studies, systematic reviews, and qualitative studies.
  • Quality assessment (RoB2) and narrative synthesis by age and intervention type.

Main Results:

  • Developmentally targeted interventions (e.g., therapeutic play, CBT) improve emotional regulation, cognitive function, and social adjustment.
  • Interventions show promise in enhancing outcomes for children with cancer.
  • Sample heterogeneity and varied measurements limit generalizability.

Conclusions:

  • Integrating a developmental perspective enhances psychosocial intervention effectiveness in pediatric oncology.
  • Future research should prioritize long-term, culturally sensitive programs.
  • Implementation of evidence-based programs into clinical practice is recommended.
Abstract

Keywords:
adolescencecancer survivorshipchild developmentcognitive–behavioral therapydevelopmental stagesemerging adulthoodpediatric oncologypsychosocial interventionsresilienceschool re-entry

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