Related Experiment Video
Updated: May 3, 2026

11:19
Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
12.2K
Development of Antibacterial Dentures Using Titanium Apatite Peening
Hideaki Sato1, Akiko Miyake2, Nichika Harakawa3
1Department of Mechanical Engineering, Faculty of Science and Engineering, Tokyo City University, 1-28-1 Tamadutsumi, Setagaya-ku, Tokyo 158-8557, Japan.
Bioengineering (Basel, Switzerland)
|February 27, 2026
Summary
This study developed antibacterial dentures by coating polymethyl methacrylate (PMMA) with titanium apatite. Lowering the coating speed significantly improved antibacterial effectiveness against Staphylococcus aureus.
Area of Science:
- Biomaterials Engineering
- Dental Materials Science
- Surface Chemistry
Background:
- Dental plaque accumulation on dentures can lead to infections.
- Polymethyl methacrylate (PMMA) is a common denture base material.
- Incorporating antibacterial agents into denture bases can enhance oral hygiene.
Purpose of the Study:
- To investigate the fabrication of antibacterial dentures using titanium apatite peening on PMMA.
- To evaluate the effect of peening parameters on titanium apatite deposition and antibacterial properties.
- To assess the clinical applicability of the developed antibacterial denture base material.
Main Methods:
- Titanium apatite was peened onto PMMA specimens using varying mass flow rates (1, 2, 5 g/s) and total peening masses (5, 10, 15 g).
- Surface morphology, elemental distribution, and mass changes were analyzed.
- Antibacterial activity against Staphylococcus aureus was assessed using a crystal violet assay.
Main Results:
- A lower peening mass flow rate (1 g/s) resulted in increased titanium apatite deposition and enhanced antibacterial properties.
- Total peening mass did not significantly influence deposition or antibacterial activity.
- The surface roughness of the PMMA remained unchanged, indicating suitability for clinical use.
Conclusions:
- Peening titanium apatite onto PMMA at a reduced mass flow rate improves bonding and antibacterial efficacy.
- This method offers a promising approach for developing novel antibacterial denture base materials.
- The findings suggest potential for improved denture hygiene and reduced infection risk.
Related Concept Videos
iChip
105
The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...
105
Development of the Oral Microbiota
65
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
65

