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Updated: Jun 29, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
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Cervical Adenocarcinoma In Situ in Young Nulliparous Patient with Persistent ASC-US and Multiple-Type HPV Infections

Nikola Milic1, Marija Varnicic Lojanica1, Stefan Ivanovic2

  • 1Užice General Hospital, 31000 Užice, Serbia.

Diagnostics (Basel, Switzerland)
|February 27, 2026
PubMed
Summary

Adenocarcinoma in situ (AIS) is a severe cervical premalignant lesion often linked to persistent human papillomavirus (HPV) infection. This case highlights challenges in detecting glandular lesions, emphasizing caution with persistent low-grade cervical abnormalities, especially in younger patients.

Keywords:
ASC-USadenocarcinoma in situcervix uterihuman papillomavirus

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