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MiMics-Net: A Multimodal Interaction Network for Blastocyst Component Segmentation
Adnan Haider1, Muhammad Arsalan2, Kyungeun Cho1
1Department of Computer Science and Artificial Intelligence, College of Advanced Convergence Engineering, Dongguk University-Seoul, 30 Pildongro 1-gil, Jung-gu, Seoul 04620, Republic of Korea.
Diagnostics (Basel, Switzerland)
|February 27, 2026
Summary
A new AI model, MiMics-Net, accurately segments human blastocyst components for improved in vitro fertilization (IVF) success. This advanced segmentation overcomes limitations of current methods, offering a more reliable assessment for predicting pregnancy outcomes.
Area of Science:
- Reproductive medicine
- Artificial intelligence in healthcare
- Medical image analysis
Background:
- Global infertility rates are rising, increasing demand for effective assisted reproductive technologies.
- In vitro fertilization (IVF) success relies heavily on accurate blastocyst assessment, a currently manual, subjective, and error-prone process.
- Existing AI segmentation methods struggle with challenging blastocyst image conditions like low contrast and texture similarity.
Purpose of the Study:
- To develop a novel AI-based segmentation network for accurate blastocyst component analysis.
- To address limitations of current methods in handling complex image data and improve IVF success prediction.
Main Methods:
- Developed MiMics-Net, a lightweight multimodal interaction segmentation network.
- Utilized a multimodal blastocyst stem processing photometric intensity, local textures, and directional orientation.
- Incorporated dual-path grouped blocks and a lightweight refinement decoder for enhanced feature processing and spatial restoration.
Main Results:
- MiMics-Net achieved a Jaccard index score of 87.9% on a human blastocyst dataset.
- The model requires only 0.65 million trainable parameters, indicating computational efficiency.
- The multimodal approach and network architecture improved segmentation performance over existing methods.
Conclusions:
- MiMics-Net offers a promising AI solution for accurate blastocyst segmentation in IVF.
- The developed network effectively handles challenging image conditions, paving the way for more reliable IVF outcomes.
- This lightweight and efficient model can enhance the precision of assisted reproductive technologies.

