Related Experiment Video
Updated: Feb 28, 2026

07:35
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
8.1K
Breast Cancer Classification Using Feature Selection via Improved Simulated Annealing and SVM Classifier.
Maedeh Kiani Sarkaleh1, Hossein Azgomi1, Azadeh Kiani-Sarkaleh2
1Department of Computer Engineering, Ra.C., Islamic Azad University, Rasht 4147654949, Iran.
Diagnostics (Basel, Switzerland)
|February 27, 2026
Summary
This study introduces an automated computer-aided diagnostic (CAD) system for breast cancer detection using mammograms. The system utilizes an Improved Simulated Annealing (ISA) algorithm for feature selection, significantly enhancing diagnostic accuracy.
Area of Science:
- Medical Imaging
- Artificial Intelligence in Healthcare
- Oncology
Background:
- Breast cancer is a leading cause of mortality in women, necessitating early detection for improved outcomes.
- Computer-aided diagnostic (CAD) systems are vital for enhancing mammogram analysis accuracy and expediting clinical decisions.
Purpose of the Study:
- To develop an automated CAD system for detecting cancerous tumors in mammograms.
- To improve the accuracy and efficiency of breast cancer diagnosis through advanced feature selection and classification techniques.
Main Methods:
- An automated CAD system comprising preprocessing, feature extraction, feature selection (Improved Simulated Annealing - ISA), and classification (Support Vector Machine - SVM).
- Preprocessing involved ROI extraction, noise suppression, and contrast enhancement.
- ISA algorithm adaptively selected informative features using a composite fitness function to reduce dimensionality while maintaining accuracy.
Main Results:
- The system achieved high performance on CBIS-DDSM and MIAS datasets, with accuracies of 99.67% and 98%, respectively.
- Sensitivities reached 99.33% and 98%, and F1-scores were 99.66% and 97.9%, respectively.
- The ISA algorithm demonstrated superior performance compared to traditional Simulated Annealing and full-feature methods.
Conclusions:
- The ISA algorithm is effective in selecting relevant features for breast cancer detection.
- The proposed CAD system significantly enhances diagnostic performance in mammogram analysis.

