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Exploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry
Yinuo Liu1,2, Qiuxiao Li1,2, Ruijia Liu1,2
1School of Food and Health, Beijing Technology and Business University, Beijing 100048, China.
Foods (Basel, Switzerland)
|February 27, 2026
Summary
Betaine is a versatile zwitterion moving beyond agriculture and nutrition. Its unique structure is driving innovation in green chemistry, materials science, and sustainable industrial processes.
Area of Science:
- Green Chemistry and Materials Science
- Biochemistry and Biotechnology
Background:
- Betaine historically functions as an osmoregulator in agriculture and a methyl donor in animal nutrition.
- Recent research highlights betaine's potential in green chemistry and materials science due to its unique physicochemical properties.
Purpose of the Study:
- To review the expanding applications of betaine, connecting its biological roles with emerging technological uses.
- To analyze research trends in betaine applications through bibliometric analysis, focusing on industrial ecology and advanced materials.
Main Methods:
- Comprehensive literature review of betaine applications.
- Bibliometric analysis to map research evolution and trends.
- Synthesis of current advancements and future directions in betaine utilization.
Main Results:
- Betaine is being repositioned for advanced applications beyond its traditional roles.
- Emerging applications include deep eutectic solvents (DESs), cocrystal engineering, and sustainable polymer synthesis.
- Bibliometric analysis reveals a growing research focus on industrial ecology and advanced materials.
Conclusions:
- Betaine is a versatile molecular component with significant potential in sustainable materials and chemical engineering.
- Its unique structure supports applications in biomedicine, food science, and industrial formulations.
- Future research should explore betaine's role in developing eco-friendly technologies and advanced materials.
Keywords:
betainebibliometric analysiscocrystalsdeep eutectic solvents (DESs)green chemistrytraditional applicationsMore Related Videos
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