Posidonia oceanica (L.) Delile in Focus: In Vitro and In Vivo Evidence for Biomedical Potential

Area of Science:

• Marine Biology
• Pharmacology
• Phytotherapy

Background:

• Posidonia oceanica, a Mediterranean endemic seagrass, is recognized for ecological importance and bioactive compound potential.
• Diverse constituents like polyphenols, peptides, and polysaccharides have been identified in P. oceanica.

Purpose of the Study:

• To review the identified bioactive compounds in Posidonia oceanica.
• To explore the therapeutic potential and applications of P. oceanica extracts in human health, pharmaceuticals, and cosmeceuticals.

Main Methods:

• Review of scientific literature on P. oceanica constituents and their activities.
• Analysis of in vitro and in vivo studies demonstrating cellular process modulation.
• Assessment of recent advances in delivery technologies for P. oceanica extracts.

Main Results:

• P. oceanica compounds exhibit antioxidant, anti-inflammatory, cytotoxic, and metabolic regulatory activities.
• Demonstrated influence on apoptosis, autophagy, and enzyme inhibition suggests promise for cancer, skin aging, and metabolic disorders.
• Enhanced bioavailability through nanoparticles, micelles, and liposomes improves pharmaceutical and cosmeceutical applications.

Conclusions:

• Posidonia oceanica represents a significant source for marine phytotherapy, bridging traditional use with scientific validation.
• Antimicrobial and antibiofilm properties suggest applications in food preservation and infection control.
• Further research is needed to translate preclinical findings into clinical applications and ensure sustainable resource management.