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Semi-Automated Lung Segmentation Based on Region-Growing Methods in Interstitial Lung Disease
Mădălin-Cristian Moraru1,2, Cristiana-Iulia Dumitrescu3, Suzana Măceș2,4,5
1Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Journal of Clinical Medicine
|February 27, 2026
Summary
This study introduces a semi-automated lung segmentation method using region-growing algorithms for computed tomography (CT) scans. The technique accurately delineates lung boundaries, balancing automation with user control for pulmonary disorder analysis.
Area of Science:
- Medical Imaging
- Radiology
- Pulmonary Medicine
Background:
- Computed tomography (CT) is essential for diagnosing pulmonary disorders.
- Quantitative CT analysis, crucial for conditions like fibrosis, necessitates accurate lung segmentation.
- Manual segmentation is laborious and subjective; automated methods can be unreliable.
Purpose of the Study:
- To develop and evaluate a semi-automated lung segmentation method for CT images.
- To address the limitations of manual and fully automated segmentation techniques.
- To improve the efficiency and accuracy of lung segmentation in computer-aided diagnosis (CAD) systems.
Main Methods:
- Implementation of a region-growing algorithm for lung segmentation.
- Development of a semi-automated approach balancing automation and user interaction.
- Testing and validation of the segmentation method on a software platform.
Main Results:
- The proposed semi-automated method effectively delineates lung boundaries in CT scans.
- The region-growing approach balances automation with necessary user control.
- The technique minimizes both computational complexity and manual effort required for segmentation.
Conclusions:
- The developed semi-automated lung segmentation technique provides accurate delineation of lung boundaries.
- This method offers an efficient alternative to manual segmentation for quantitative CT analysis.
- The approach is suitable for CAD systems in diagnosing pulmonary diseases like COPD, pneumonia, and lung cancer.

