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Updated: Feb 28, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
Perioperative Factors and Radiographic Brixia Scores' Effect on Early Extubation After Fallot Tetralogy Surgery
İbrahim Akkoç1, Selin Sağlam1, Ezgi Direnç Yücel1
1Department of Anaesthesiology and Reanimation, Saglik Bilimleri University, Basaksehir Cam and Sakura Hospital, Istanbul 34480, Turkey.
Abstract:
Introduction and Objective: This study aims to evaluate the effect of perioperative factors and radiographic Brixia scores on early extubation following corrective surgery for Fallot tetralogy at a high-volume single cardiac center. Materials and Methods: A retrospective evaluation was conducted on 120 cases who underwent complete correction due to Fallot tetralogy [Median age 6 months (IQR 5-7), Median weight 6.2 kg (IQR 5.2-8 kg)]. Patient demographics, preoperative characteristics, intraoperative variables, postoperative outcomes, surgical type, surgical duration, cardiopulmonary bypass (CPB) time, cross-clamp time, and blood product volumes were retrieved from electronic medical records. P/F ratio, PaO2/FiO2, and Oxygen Index (OI) were calculated. Early extubation was defined as extubation occurring within 6 h after the completion of surgery. The Brixia score (Interstitial opacities, 1 point; interstitial predominant alveolar, 2 points; and interstitial and alveolar opacities, 3 points) was graded for both lung lobes divided into three segments, with a total score ranging from 0 to 18. The results were analyzed statistically. Results: In 60% of the cases (n = 72), valve-preserving surgery was performed, and in 40% (n = 48), a transannular patch was used. The early extubation rate was 20% (n = 24). The median duration of mechanical ventilation was 10 h (IQR, 6-15). Older age (median 8 vs. 5 months), valve-preserving surgery, lower incidence of right-to-left shunt Patent Foramen Ovale (63% vs. 84%), higher P/F ratio on ICU admission (360 vs. 220), and lower Brixia scores on ICU admission (8 vs. 11) and on postoperative day 1 (7 vs. 12) were identified as significant factors for early extubation (p < 0.05). The mortality rate in the entire patient group was 3.3%. In multivariable logistic regression analysis, older age (OR: 1.2, 95% CI: 1.1-1.9 p = 0.03), valve-sparing repair (OR: 1.7, 95% CI: 1.2-2.5, p = 0.008), and lower postoperative Brixia scores (OR:1.4 95% CI: 1.2-2.1, p = 0.02) remained independently associated with early extubation. Conclusions: The Brixia score can be used as a reliable scoring system for evaluating postoperative lung status. Pulmonary valve-preserving repair shows a profile of earlier lung parenchyma recovery compared to transannular patch repair.
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