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Prevotella-Based Bacterial Mixture Influences Gut Microbiota Composition in Weaned Piglets
Jitka Matiasovicova1, Daniela Karasova1, Alena Sebkova1
1Veterinary Research Institute, 621 00 Brno, Czech Republic.
Microorganisms
|February 27, 2026
Summary
A novel Prevotella-based bacterial mixture shows potential as a probiotic for weaned piglets. Early administration modulated gut microbiota composition, increasing beneficial bacteria and suggesting improved gut health.
Area of Science:
- Animal Science
- Microbiology
- Gastroenterology
Background:
- Gut microbiota shifts occur in weaned piglets.
- Prevotella species are known to influence gut health.
Purpose of the Study:
- To evaluate a Prevotella-based bacterial mixture as a novel probiotic for weaned piglets.
- To determine the impact of this probiotic on gut microbiota composition.
Main Methods:
- Oral administration of a Prevotella mixture to experimental piglets on weaning day.
- 16S rRNA sequencing of rectal swabs from control and experimental piglets at weaning and one week post-weaning.
Main Results:
- Prevotella mixture bacteria were detected in experimental piglets' gut microbiota.
- Lactobacillaceae and Lachnospiraceae families were more abundant in experimental piglets.
- Pasteurellaceae, Coriobacteriaceae, Bacteroidales RF16 group, and Methanobacteriaceae were more abundant in control piglets.
Conclusions:
- Early administration of the Prevotella mixture significantly affected gut microbiota composition in weaned piglets.
- This bacterial mixture may serve as a novel approach to enhance gut health in weaned piglets.
